However, since residual herbicides generally don't last more than three weeks even with sufficient rainfall, proactivity — staying ahead of the weed from burn down to lay-by — is another critical factor in dominating pigweed.

Walt Corcoran, who farms a few miles north of Eufaula in the southeastern corner of Alabama, follows a proactive strategy that has set the standard for growers in the rest of the state, Patterson says.

Corcoran puts Gramoxone and Diuron down two weeks ahead of planting, which kills emergent pigweed, then plants Roundup Ready cotton," Patterson says.

At planting, he applies Reflex alone or with Prowl and hopes for rain. Both of these herbicides have soil‑residual effects against pigweed.

Two to three weeks later, this is followed by an over-the-top application of either Dual or Warrant plus glyphosate (Roundup).

The key, Patterson stresses, is to apply this mixture before the pigweed re-emerges.

Three to four weeks later, Corcoran runs a hooded sprayer in the middles with Gramoxone.  

This is followed with a lay-by application containing Valor plus MSMA or glyphosate which provides additional residual effect.

As pigweed continues its relentless spread throughout Alabama and the rest of the South, Patterson says producers who have detected pigweed in Roundup Ready cotton fields must follow similar regimens.

Some companies are stepping up with the development of cotton varieties genetically modified for additional herbicide resistance and that will provide growers with more options.

Two of the most promising new technologies include Monsanto's dicamba-tolerant cotton, and Dow's new line of cotton resistant to 2 4-D applications.

"Both of these will secure a measure of control over pigweed," Patterson says. "It won't ensure they're graveyard dead, but they will provide at least 80 percent control when used alone and even better when used with glyphosate or Liberty (gluphosinate)."

The bad news is neither of these varieties will be available for the next four years.

“Bayer is coming out this year with their GlyTol-LibertyLink varieties that allow the application of glyphosate and Liberty and this will help right now,” he says.

Patterson says another promising area of research has focused on high‑residue cropping systems: planting a rye cover crop, rolling it down, and then planting no-till cotton into the rye. The rye deprives pigweed seed of critically needed sunlight.

"This system works," he says. "The problem is that in high-acreage systems it's hard to manage."

While rotation is another option, consistent, proactive soil-residual herbicide applications to reduce seed populations will remain the best strategy for most producers.

"To do that, you've got to maintain complete control for three years," Patterson says. "Even if half of this seed ends up rotting in the soil each year, you're still faced with a tremendous problem."